Registered: Jun 2003
Location:
Posts: 415

Posted on the FDA website 9/20/18:

The U.S. Food and Drug Administration is alerting pet owners and veterinarians to be aware of the potential for neurologic adverse events in dogs and cats when treated with drugs that are in the isoxazoline class.

Since these products have obtained their respective FDA approvals, data received by the agency as part of its routine post-marketing activities indicates that some animals receiving Bravecto, Nexgard or Simparica have experienced adverse events such as muscle tremors, ataxia, and seizures. Another product in this class, Credelio, recently received FDA approval. These products are approved for the treatment and prevention of flea infestations, and the treatment and control of tick infestations.

The FDA is working with manufacturers of isoxazoline products to include new label information to highlight neurologic events because these events were seen consistently across the isoxazoline class of products.

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Registered: Sep 2010
Location: New Paris, Indiana
Posts: 7076

I have used all three products on my hounds since they came out and have never observed any adverse reactions. I have a feeling the majority of these problems are probably with the foo foo breeds. These tiny toy breeds that are so popular today react to everything.

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Registered: Aug 2004
Location: Chattanooga, Tn
Posts: 22462

We have just discovered after 4 years that our dog's Erlichia flare ups corresponded with the administration of Bravecta. Flare ups were blamed on hot weather but while examining records found that Bravecta was started when weather started getting hot. When looking over Vet's records it was discovered that Doxy was always prescribed 2 weeks after Bravecta was given. Can it be a coincidence when it happens 4 years in a row?

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Registered: Aug 2003
Location: S. Ga.
Posts: 4608

Have used it for several years with no problems, but was warned by the vet that it could cause those problems.

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Registered: Aug 2006
Location: Northwest Mississippi
Posts: 774

quote:

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Originally posted by Richard Lambert
We have just discovered after 4 years that our dog's Erlichia flare ups corresponded with the administration of Bravecta. Flare ups were blamed on hot weather but while examining records found that Bravecta was started when weather started getting hot. When looking over Vet's records it was discovered that Doxy was always prescribed 2 weeks after Bravecta was given. Can it be a coincidence when it happens 4 years in a row?

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John Walker

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Registered: Nov 2004
Location: tennessee
Posts: 856

You can check the results by not giving the bravecto next year. It may be the medication or it may just be the heat.

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Registered: Aug 2006
Location: Northwest Mississippi
Posts: 774

quote:

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Originally posted by johnny reb
You can check the results by not giving the bravecto next year. It may be the medication or it may just be the heat.

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John Walker

PKC CH GRNITECH GRCH 'PR' Southern Farms Jeb
GRNITECH GRCH 'PR' Southern Farms Pearl
UKC NITECH AKC NITECH 'PR' Southern Farms Independence
'PR' Southern Farms Bohannon

Gone But Not Forgotten:
UKC NITECH GRCH AKC NITECH 'PR' Southern Farms Bocephus
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Registered: Aug 2004
Location: Chattanooga, Tn
Posts: 22462

Don't worry, he will never get any more Bravecto.

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Registered: Apr 2014
Location: batsville ark
Posts: 1110

used on a dog that comes down with a thyroid problem brain seizures can be so frequent and severe your dog will have to be put to sleep. r.i.p. collectors penny . dead at 18 months old .their is no antidote for the poison pill once it is ingested. kill times for ticks is to slow on ticks and transfer time for disease tick to dog has been proven to be as little as 2 hours so why feed the poison and take unnecessary risk? i rung the alarm bell on the poison pills long ago. lol just like the factual info on thyroids and the hereditary problems in our hounds no one listens to this crazy old fool anyhow. lol

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Registered: Apr 2014
Location: batsville ark
Posts: 1110

p.s. if you are ivomec or any heartworm preventive with it as the ingredient dont be shocked when you have a heart worm positive dog in the pen . treating my first positive hound in 40 years .

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Registered: Jun 2007
Location: jacksonville, nc
Posts: 2856

So, after all these years of using ivermectin for heart worm prevention, you're saying the ivermectin is bad for a dogs health or that it doesn't work?

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Registered: Jun 2003
Location:
Posts: 415

"So, after all these years of using ivermectin for heart worm prevention, you're saying the ivermectin is bad for a dogs health or that it doesn't work?"

There are 2 parts to your question....First, from what I have read on some of the veterinary websites & information pages, there ARE some areas of the country where the heartworm microfilaria do seem to be developing some resistance to the heartworm medications being used. There have been more dogs testing positive for HW in recent years, even though their owners claim that their dogs have been on the preventative all year round. But one article pointed out that it is possible that some of these dogs' owners may have forgotten to give the medication, or it may have been given, but the dog threw it up without the owner's knowledge. So there is some question as to what is really going on.

Regarding Bravecto, Nexgard, & Simparica - These products are approved for the treatment and prevention of FLEA infestations, and the treatment and control of TICK infestations. Credelio is newly-approved by the FDA for the SAME purpose, and it is a drug in the same class as the other 3. THESE drugs are the ones that the FDA is now warning us about.

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Registered: Jun 2003
Location: Oakdale, Pennsylvania
Posts: 3753

is the active ingredients in these ??

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Registered: Jun 2003
Location:
Posts: 415

ISOXAZOLINE.

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Registered: Apr 2014
Location: batsville ark
Posts: 1110

quote:

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Originally posted by croatankid
So, after all these years of using ivermectin for heart worm prevention, you're saying the ivermectin is bad for a dogs health or that it doesn't work?

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Registered: Jun 2007
Location: jacksonville, nc
Posts: 2856

Littletown, Yes, I've read and heard the same.

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Registered: Jun 2017
Location: South ga
Posts: 13

Are fhere any long term affects found after taking the dogs off of Bravecto?

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