Rip
UKC Forum Member
Registered: Jun 2003
Location: Morrison TN
Posts: 4927 |
That's exactly what inbreeding is for, to make your sandbox small enough to control what's in it so you can put in or take out what you need to. Also, yes they do have to have a certian number of genes, but genes are made up of nucleic acids and while all dogs have the same number of genes the order of the acids makes it unique. You don't get rid of EVERY gene of the one you are selecting against, just the one particular gene with that particular acid sequence. So you are getting rid of gene 3-33333333, you still keep a copy of gene 3 in your line, but it does not have the -33333333 sequence that made it cause the disease. That -33333333 sequence is eliminated.
That's the whole point. This was an actual true life example that someone I know faced.
As for the other things, we don't know the exact linkages or which genes do what, probably never will. Heck there is no telling how many genes it takes just to make up a dogs voice, or it's tree desire etc. It could be in the thousands. We do however know the basic parameters of the modes of inheritance of all genes (at least we think we do).
However, through strict selection criteria and culling practices you can make better, more uniform strides through inbreeding and linebreeding than any other way. It produces the most consistant, most predictable results there are. So the breeder isolates exactly the kind of dog he wants but doesn't know which 1000 genes he has going for him. Does it really matter as long as it worked?
The only reason we know so much about hemophelia is becasue it is X linked recessive and is easy to study, however when they first removed it from lines they didn't have any clue which gene it was, only that they had sucessfully eliminated it from that line. Years later they realized just which gene they removed. They were able to remove it not because of knowing which gene it was, but by strict culling and selection and inbreeding.
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Last edited by Rip on 01-31-2006 at 02:38 AM
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