Plottluvr
UKC Forum Member
Registered: Dec 2006
Location: Two Rivers WI
Posts: 996 |
Bloodroot extracts are toxic to animal cells
Sanguinarine kills animal cells by blocking the action of Na+/K+-ATPase transmembrane proteins. As a result, applying bloodroot to the skin may destroy tissue and lead to the formation of a large scab, called an eschar. Bloodroot and its extracts are thus considered escharotic.
In spite of supposed curative properties and historical use by Native Americans as an emetic, internal use is inadvisable. Although applying escharotic agents, including bloodroot, to the skin is sometimes suggested as a home treatment for skin cancer, these attempts can be severely disfiguring.[5] Salves derived from bloodroot cannot be relied on to remove an entire malignant tumor. Microscopic tumor deposits may remain after visible tumor tissue is burned away, and case reports have shown that in such instances tumor has recurred and/or metastasized.
On 13 Aug 2005, U.S. news media reported that Dan Raber (of Georgia, United States) came under felony investigation for dispensing bloodroot paste to women with various ailments including breast cancer. It was reported that nine women developed disfiguring destruction of skin and underlying tissue. Reports also indicated that Lois March, M.D., who is a practicing physician in Cordele, Georgia, has also come under U.S. FDA investigation for her role in prescribing pain medication to Raber's disfigured customers while their use of bloodroot was ongoing.
Commercial use of sanguinarine and bloodroot extracts
The United States FDA has approved the inclusion of sanguinarine in toothpastes as an antibacterial or anti-plaque agent. Currently, it is believed that this use may cause leukoplakia, a premalignant oral lesion. On 24 Nov 2003, the Colgate-Palmolive Company of Piscataway, New Jersey, United States commented by memorandum to the United States Food and Drug Administration that then-proposed rules for levels of sanguinarine in mouthwash and dental wash products were lower than necessary. However, this conclusion is controversial.
Some animal food additives sold and distributed in Europe such as Phytobiotics' Sangrovit contain sanguinarine and chelerythrine. On 14 May 2003, Cat Holmes reported in Georgia Faces that Jim Affolter and Selima Campbell, horticulturists at the University of Georgia College of Agricultural and Environmental Sciences, were meeting with Phytobiotics to relate their research into commercial cultivation of bloodroot. It is also used in the mole remover Dermatend.
Bloodroot extracts have also been promoted by some supplement companies as a treatment or cure for cancer, but the U.S. Food and Drug Administration has listed some of these products among its "125 Fake Cancer 'Cures' Consumers Should Avoid".
Virginia Snakeroot
Medicinal Properties
Anodyne, antispasmodic, diaphoretic, bitter tonic, nervine, stimulant
Uses
Small doses will stir a poor appetite, and promote proper digestion, but large doses will cause vomiting, diarrhea , vertigo, and other unpleasant effects. In proper doses it is said to stimulate blood circulation, reduce fever, stomachache, smallpox, scarlet fever, pneumonia, croup, flatulence, suppressed menses. The tea gargled for sore throats. At one time, this herb was perhaps the most highly valued of snakebite remedies, various other species of its genus also being used in different parts of the world for the same purpose. Native Americans treated snakebite by cutting into the bite and sucking out the poisonous venom, then applying the chewed root of the plant to the wound.
Formulas or Dosages
Infusion: steep 1 tsp. dried rootstock and roots in 1 cup boiling water. Take 1 tbsp. 3 to 6 times per day.
Tincture: a dose is from 1 to 20 drops, taken in cold water. Use with caution.
Warning
Virginia snakeroot contains an alkaloid which, in pure form, can paralyze the respiratory system. Use only small doses of the plant; and with medical supervision if possible. Too rare to harvest.
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