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-- Ivermectine Question??????????? (http://forums.ukcdogs.com/showthread.php?threadid=470713)
Ivermectine Question???????????
I have some extra cash and wanted to buy some ivermec, but noticed they had ivermec and ivermec plus whats the difference?? what do ineed to buy for my beagles? how much per pound of body weight ? a vet once told me how much to administer but i have forgot , if we have any one with expierence with worming dogs with ivermec please let me know what i need to buy and how much to give??? thanks
ivermec DONT use the plus. It is 1/10 cc per 10 lbs
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When i had tree dogs i gave this under the skin,one guy told me he gave it by mouth how do you prefer to give ivermec??
like PLATT said --NO +---I pull out the amount you need and fill the remaining with --pop -juice any thing to help the taste --ivomec -is bitter
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ALLNITER DOUG CHEEK
ALWAYS GO BY THE RULES AND NEVER A PROBLEM
I give 1 tenth of a cc per 10lbs orally. I have done it for years with no problems. After i draw it out of the bottle I take the needle off and suck a little stale pop in it and squirt it in the back of their mouth and let them swallow.
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Cheat Mountain, WV (Gods Country)
thanks for the advice i would have never thought of using something to take the edge off the taste
You only want to use it 9 months out of the year....I use it April through December. I also cut the dose to .5 for every 10 lbs. This stuff works great but is extremely hard on the liver! Last thing I want to do is kill my dog. Make sure your dog is checked for heart worm before you use it....if it has heart worm you will kill the dog!
I give mine subQ......no need to mess with pop, kool aid, etc....
Now.....you can also buy the horse wormer with ivomec and use that once a month on an adult dog. This covers everything. Give it in a pea sized dose. Look into this a little and do some research.
Steve
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sanfordssj
Hey i heard about useing the horse wormer with ivomec with the dogs look at it alot but just never bought any i have seen that there is like 3 to 4 different kinds witch one do you use . This seem to be the best way to go i have gave my dog ivomec for years and have no problems with it or with the dogs being on it and taking that much i give my dogs 3/10 of a cc year round and have never miss a month but something i do also is once a year i take my dogs in to the vet to have heartworm test done on them and every year i come back from the vet with dogs heart worm free . Thanks Jimmy Leach
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I have the same trouble when i go to get worm meds,just dont know what to buy, with that being said if its possible could someone post a pic of what they buy or at least a link to help people get the right worm meds??
Gameover
I use Happy Jacks Deworming Liqui-vict 2x Liquid Dewormer and for my pup`s i use Happy Jacks Puppy Paste Wormer i have use Happy Jacks ever since i own beagles and wouldn`t use anything else . Thanks Jimmy Leach
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CJ`S SOUTHERN TOPNOTCH BEAGLES HOME OF THE YA YA SISTER`S ((( IN RETIREMENT ))) AND 2009 UKC WORLD QUALIFIER. CJ`S TOPNOTCH ( BILLY ) THE KID AND 2011 `CJ`S`CH`PR` TOPNOTCH MAD HUNTIN ( MACY ) CJ`S TOPNOTCH ( FLY ) BLY`CJ`S TOPNOTCH HOLLYWOOD ( TOUGH ) `CJ`S TOPNOTCH MISTER GOOD TIME ( ROWDY ) ` CJ `S TOPNOTCH SOUTHERN ( BELL ) `CJ`S TOPNOTCH KING`S ( KATIE ) `CJ`S TOPNOTCH MISS ARKANSAS ( REBA ) `CJ`S TOPNOTCH CAPTAIN ( CHAOS ) `CJ`S TOPNOTCH MISTER ( TIPTON ) CJ`S TOPNOTCH PISTOL ( ANNIE ) CJ`S TOPNOTCH ( SAMMY ) SWEET HEART " CJ` S TOPNOTCH MISTER BOJANGLES CJ`S SOUTHERN TOPNOTCH DOC HOLLIDAY THE WINNER AIN`T THE ONE WITH THE BEST DOG IT`S THE ONE WHO REFUSE TO LOSE."
quote:
Originally posted by sanfordssj
You only want to use it 9 months out of the year....I use it April through December. I also cut the dose to .5 for every 10 lbs. This stuff works great but is extremely hard on the liver! Last thing I want to do is kill my dog. Make sure your dog is checked for heart worm before you use it....if it has heart worm you will kill the dog!!
Steve
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I agree Ivomec itself will not kill a dog, unless the dog already has heart worms. It is not the Ivomec that kills the dog but the dead worms will plug or cause the blood flow to stop and that's what kills the dog. I also use 1/10 of one cc per ten pounds of body weight for prevention of heart worms, pups under the age of 6 months shouldn't have heart worms so I treat them with no worries. If over 6 months they should be checked for heart worms before using Ivomec for treatment of heart worms. I have used Happy Jack Liqui-Vict 2X or Nemex 2 they are the same. Panacur paste for horses is also a good wormer. I put about a 1 inch line on top of their feed or inject directly in the mouth. By the way the Ivomec is the inject-able kind for cattle, but put in dogs mouth not under the skin.
I buy the horse wormer , called Equimax , at TSC. It is about $13 and is good for about 1300lbs. I use this brand because it has the ingredient for tape worms in it. The plunger on the syringe is marked at 100 lb. increments so you can get fairly close on weight. Been using it for about 6 years now with no problems at all.
I was checking out the beagle site because my son has gotten into the beagles this past year. i have hunted big game for 25 years. A buddy of mine was told by a older man and he read it some where also. But we give the ivermectin under the skin between the shoulder blades. It not only take care of the heartworm but also the fleas. we haven't had any flea problems since we started doing this. Why it works i don't know. try to read up on it. Don't just take my word for it. But it works for us.
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quote:
Originally posted by bluetickbiggame
I was checking out the beagle site because my son has gotten into the beagles this past year. i have hunted big game for 25 years. A buddy of mine was told by a older man and he read it some where also. But we give the ivermectin under the skin between the shoulder blades. It not only take care of the heartworm but also the fleas. we haven't had any flea problems since we started doing this. Why it works i don't know. try to read up on it. Don't just take my word for it. But it works for us.
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this is the best information i have found and keep on file:
Ivomec Dosage Instructions for Heartworm Prevention
I don't endorse the extra-label use of liquid ivermectin for dogs, but I'm concerned that people are using it improperly, subjecting their dogs to potentially dangerous levels (for some dogs) of ivermectin. See below for information on how to properly dilute Ivomec 1% solution in order to make it safe to use for dogs. You can use 0.08% sheep drench undiluted.
I have also worked out the amount of ivermectin in Acarexx, used to treat ear mites in cats (and off-label in dogs), which might be useful for people who cannot otherwise afford to treat a large number of dogs. Contact me privately for more information (my contact information is at the bottom of the page).
Contents
Introduction
Ivermectin Sensitivity
Ivermectin Efficacy
Directions for using 0.08% sheep drench
Directions for Making 30:1 Dilution of 1% solution
Directions for Making 9:1 Dilution of 1% solution
Directions for using Ivermectin powder
Buy Ivermectin, Propylene Glycol and Glycerin
About J&R Enterprises Ivermectin Blend
How the Calculations Were Done
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Disclaimer: I am not a veterinarian, nor do I have any formal training in any medical field. The information presented here is not meant to replace your vet's advice or prescribed medications, but only to suggest additional options to explore, based on your dog's condition.
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Introduction
Liquid ivermectin (Ivomec) is available in 1% injectable solution for treating cattle and pigs, and in 0.08% oral solution for treating sheep (the 0.27% solution has been discontinued). In most cases, you will need a syringe (no needle) that measures to the tenth of a cc to administer. Note that all of these products are given orally.
Ivermectin 0.08% solution made for sheep can be used undiluted. An 8 oz (236 ml) bottle of ivermectin 0.08% solution costs around $28, and would be enough to treat 70,000 pounds of dogs.
Ivermectin 1% solution is more readily available but cannot be used undiluted even for very large dogs. Without diluting the ivermectin solution, the amount to give is too small to measure accurately. The proper way to use liquid 1% ivermectin solution for dogs is to dilute the ivermectin with propylene glycol (or possibly food-grade (USP) glycerin -- I have not actually seen instructions using glycerin rather than propylene glycol, but liquid ivermectin injectable solutions are made with 40% glycerol and 60% propylene glycol). Some people have used vegetable oil instead because it tastes better and is easier to get, but the drug will not mix as well with oil and so the dosage within the solution may not be even. A 50 ml bottle of ivermectin 1% solution costs around $35 and would be enough to treat 150,000 pounds of dogs. There are instructions below for creating a 30:1 dilution, which works best for small dogs and can also be used for large dogs, and also instructions for creating a 9:1 dilution.
An Ivermectin powder product that was mixed with ground corn and designed for pigs appears to have been
See additional information below under How the Calculations Were Done.
Keep Ivomec and any unused mixture refrigerated. The length of time the diluted mixture will remain potent is unknown.
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Ivermectin Sensitivity
Note that the dosages listed below are the same as is used in Heartgard, but it's safe to give a little more. For example, when using Heartgard Green for dogs weighing 26 to 50 pounds, the dosage used is calculated for a 50-pound dog, while a 26-pound dog would get twice as much per pound of body weight. Heartgard Blue is used for dogs weighing up to 25 pounds, so a 5-pound dog would get five times as much per pound of body weight as a 25-pound dog would. Dosages as high as 50 times the amount used to prevent heartworms are used to treat mites on dogs (demodectic mange).
High dosages of ivermectin are considered safe for all dogs except those with the MDR1 gene mutation that makes them sensitive to ivermectin and other drugs. Commonly affected breeds include the Collie, Australian Shepherd (all sizes), Shetland Sheepdog, English Shepherd, Old English Sheepdog, McNab, German Shepherd, Long-haired Whippet, and Silken Windhound. There is now a test available to screen for the presence of the mutated MDR1 gene that causes this problem, see Multidrug Sensitivity for more information.
Very high doses of ivermectin, such as are used to treat demodex, are also problematic if combined with Comfortis (spinosad), a newer flea-control product that increases the risk of neurological side effects from ivermectin. Dogs infected with heartworms may suffer an anaphylactic reaction from the death of too many microfilariae at once when given very high doses of ivermectin as well.
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Ivermectin Efficacy
Recent information has come to light that Heartgard may be only 95% effective, rather than 100% effective, in preventing heartworm infections. That means it will destroy 95% of heartworm larvae, not that 95% of dogs receiving Heartgard will remain heartworm-free.
The dosage of ivermectin used in Heartgard was the lowest found to be 100% effective at killing heartworm larvae when the product was originally approved. Since lower doses were less effective, it's possible that higher doses may continue to be 100% effective.
Higher doses of ivermectin are safe for all dogs except those with the MDR1 mutation. Dosages as high as 50 times the amount used to prevent heartworms are used to treat mites on dogs (demodectic mange). Very high dosages may also be problematic for dogs infected with Heartworms, and those being treated with Comfortis. See Ivermectin Sensitivity above for more information.
It may be best to double the amount of ivermectin you give your dogs in order to potentially provide better protection from heartworm infection. Again, this does not apply to dogs with the MDR1 mutation.
Note that higher doses of ivermectin are unlikely to be more effective against the resistant strain of heartworms that has been identified in the Mississippi River Valley. Advantage Multi, which uses moxidectin, was the only product found to be 100% effective against the resistant strain in one small study. See New Information Regarding Heartworm Resistance for details.
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Directions for using 0.08% sheep drench
Dosage using Ivermectin 0.08% solution (you may want to double these doses for better protection):
up to 14 pounds: 1 drop (0.05 cc)
15 to 29 pounds: 0.1 cc
30 to 58 pounds: 0.2 cc
59 to 88 pounds: 0.3 cc
89 to 117 pounds: 0.4 cc
118 to 147 pounds: 0.5 cc
1 cc of ivermectin 0.08% sheep drench solution contains 800 mcg; 0.1 cc = 80 mcg ivermectin.
The exact dosage is 0.034 cc per 10 pounds of body weight, or approximately 0.1 cc per 30 pounds of body weight.
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Directions for making 30:1 dilution of 1% solution
Mix 30 parts propylene glycol to 1 part ivermectin 1% solution. Shake well before using to mix the ivermectin evenly. Refrigerate any unused portion.
Dosage using Ivermectin 1% solution at 30:1 dilution (you may want to double these doses for better protection):
< 6 pounds: 1 drop (0.05 cc)
6 to 12 pounds: 0.1 cc
13 to 24 pounds: 0.2 cc
25 to 36 pounds: 0.3 cc
37 to 48 pounds: 0.4 cc
49 to 60 pounds: 0.5 cc
62 to 72 pounds: 0.6 cc
73 to 84 pounds: 0.7 cc
85 to 97 pounds: 0.8 cc
98 to 109 pounds: 0.9 cc
110 to 121 pounds: 1 cc
To make a small amount of the mixture, you will need a 1 cc syringe that measures accurately to the tenth of a cc. Draw up 0.1 cc of Ivermectin solution in a 1 cc syringe, and mix well with 3 cc of propylene glycol, giving you 3 ccs at a dilution ratio of 30:1. This is enough to treat 300 pounds of dogs using the 1% solution.
To make larger amounts of the mixture, use a 1 fluid ounce dropper bottle, which is 30 ml. Put 1 ml of ivermectin solution in a 1 fluid ounce dropper bottle, then fill with propylene glycol. This will be enough to treat 3,000 pounds of dogs (e.g., 300 10-lb dogs or 150 20-lb dogs) using the 1% solution.
1 cc of ivermectin 1% diluted 30:1 contains 333 mcg; 0.1 cc = 33 mcg ivermectin.
The exact dosage is 0.0824 cc (approximately 0.1 cc) per 10 pounds of body weight.
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Directions for making 9:1 dilution of 1% solution
Mix 9 parts propylene glycol to 1 part ivermectin 1% solution. Shake well before using to mix the ivermectin evenly. Refrigerate any unused portion.
Dosage using Ivermectin 1% solution at 9:1 dilution (you may want to double these doses for better protection):
up to 18 pounds: 1 drop (0.05 cc)
19 to 36 pounds: 0.1 cc
37 to 73 pounds: 0.2 cc
74 to 110 pounds: 0.3 cc
111 to 147 pounds: 0.4 cc
To make a small amount of the mixture, you will need a 1 cc syringe that measures accurately to the tenth of a cc. Draw up 0.1 cc of Ivermectin solution in a 1 cc syringe, and mix well with 0.9 cc of propylene glycol, giving you 1 cc at a dilution ratio of 9:1. This is enough to treat 333 pounds of dogs using the 1% solution.
To make larger amounts of the mixture, use a 1 fluid ounce dropper bottle, which is 30 ml. Put 3 ml of ivermectin solution in a 1 fluid ounce dropper bottle, then fill with propylene glycol. This will be enough to treat 9,000 pounds of dogs (e.g., 90 100-lb dogs) using the 1% solution.
1 cc of ivermectin 1% diluted 9:1 contains 1,000 mcg; 0.1 cc = 100 mcg ivermectin.
The exact dosage is 0.0272 ml (approximately 0.03 cc) per 10 pounds of body weight.
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Directions for using Ivermectin powder (this product appears to have been discontinued)
Dosage using Ivermectin powder (you may want to double these doses for better protection):
up to 25 pounds: 1/8 teaspoon
26 to 50 pounds: 1/4 teaspoon
51 to 65 pounds: 1/3 teaspoon
66 to 100 pounds: 1/2 teaspoon
101 to 150 pounds: 3/4 teaspoon
Over 150 pounds: 1 teaspoon
5 grams of ivermectin power contains 1,000 mcg ivermectin.
The exact dosage is 0.136 grams per 10 pounds of body weight. The company says that 1 teaspoon weighs 5 grams, but people who have weighed a level teaspoon of the powder have found that it weighs 2.8 grams. Based on this information:
1 level teaspoon (2.8 grams) of ivermectin powder contains 560 mcg ivermectin
1/4 tsp (0.7 grams) of ivermectin powder contains 140 mcg ivermectin
Give 1/4 tsp per 50 pounds of body weight.
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Buy Ivermectin, Propylene Glycol and Glycerin
Amazon
Ivermectin 0.08% sheep drench solution, 8 oz (236 ml), $28 plus shipping.
Ivermectin 0.08% sheep drench solution, 960 ml, $57 plus shipping.
Ivermectin 1% solution, 50 ml, $29 plus shipping
Jeffers Livestock 1-800-533-3377
Ivomec 0.8% sheep drench solution, 4800 ml, $231 plus shipping (no longer offering the 960 ml size)
Privermectin 0.08% sheep drench solution, 960 ml, $50 plus shippingIvomec 1% solution, 50 ml, $34 plus shipping.
Ivermectin 1% solution, 50 ml, $32 plus shipping
Propylene glycol, 1 gallon, $20 plus shipping.
Glycerin, 1 gallon, $25 plus shipping.
Valley Vet 800-419-9524
Ivomec 0.08% sheep drench solution, 960 ml, $71 plus shipping.
Privermectin 0.08% sheep drench solution, 960 ml, $50 plus shipping
Ivomec 1% solution, 50 ml, $36 (free shipping).
Propylene glycol, 1 gallon, $19 + shipping.
Glycerin, 1 gallon, $31 + shipping.
The Chemistry Store 800-224-1430
Propylene glycol, 1 quart, $12 + shipping.
Glycerin, 1 quart, $11 + shipping.
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About J&R Enterprises ivermectin blend
Several people have contacted me about this product. The 0.0461% dilution they use would contain 461 mcg of ivermectin per 1 cc of mixture. According to the company, ivermectin is mixed with high quality propylene glycol.
The dosage they recommend is about two to three times what you would get in Heartgard, which should be safe for all dogs except possibly those with the MDR1 gene that makes them sensitive to ivermectin (see Ivermectin Sensitivity above). This dosage may even provide better protection against heartworm infection.
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How the calculations were done
Heartgard dosage is a minimum of 6 mcg/kg (2.72 mcg/lb). Note that dogs at the lower end of the weight ranges get twice this much, or even more for very small dogs. Ivermectin has a very wide safety range; dosage for dogs with demodex is 300 mcg/kg, and this amount may be given daily over weeks or months. It's important not to underdose your dog, which may not be effective at preventing heartworms. Always round up when calculating dosage.
Heartgard Blue for dogs up to 25 pounds has 68 mcg ivermectin
Heartgard Green for dogs 26-50 pounds has 136 mcg ivermectin
Heartgard Brown for dogs 51-100 pounds has 272 mcg ivermectin
Ivomec 1% solution:
1 cc of ivomec 1% contains 10,000 mcg ivermectin; 0.1 cc = 1,000 mcg ivermectin
1 cc of ivomec 1% diluted 9:1 contains 1,000 mcg ivermectin; 0.1 cc = 100 mcg ivermectin.
The exact dosage is 0.0272 ml per 10 pounds of body weight, approximately 0.03 cc per 10 pounds of body weight.
1 cc of ivomec 1% diluted 30:1 contains 333 mcg ivermectin; 0.1 cc = 33 mcg ivermectin.
The minimum dosage is 0.0824 cc per 10 pounds of body weight, approximately 0.1 cc per 10 pounds of body weight.
Ivomec 0.08% sheep drench solution:
1 cc of ivomec 0.08% sheep drench solution contains 800 mcg ivermectin; 0.1 cc = 80 mcg ivermectin.
The minimum dosage is 0.034 cc per 10 pounds of body weight, approximately 0.1 cc per 30 pounds of body weight.
Ivermectin Powder for swine:
5 grams of ivermectin power contain 1,000 mcg ivermectin
1 gram of ivermectin powder contains 200 mcg ivermectin
The minimum dosage is 0.136 grams per 10 pounds of body weight.
The company says that 1 teaspoon weighs 5 grams, but people who have weighed a level teaspoon of the powder have found that it weighs 2.8 grams. Based on this information:
1 level teaspoon (2.8 grams) of ivermectin powder contains 560 mcg ivermectin
1/4 tsp (0.7 grams) of ivermectin powder contains 140 mcg ivermectin
Give 1/4 tsp per 50 pounds of body weight.
Measurement notes:
•1 drop is approximately 0.05 cc
•cc is the same as ml
Note that you should always round the dosage up, not down. It's fine to give a little more than is needed, but if you give less, your dog may not be protected.
For the most part, larger dosages are safe, as long as your dogs are not infected with heartworms (in which case, very high doses may kill off too many microfilariae at once, which can lead to an anaphylactic reaction), or if your dogs have the mutation that makes them more susceptible to ivermectin. Even then, as long as you're close to the dosage above, you should be fine, it's just when you give 10 times as much as you should or more that you might run into trouble. This is quite common if you follow recipes on the internet, which often leave out the fact that the ivermectin must first be diluted 9:1 with another liquid, making the dosage ten times what it should be.
http://web.archive.org/web/20061104...org/katrina.htm
"Be careful when calculating doses and administering ivermectin solution, as the concentration in most available solutions is very high compared to the dose needed for small animal treatment. Remember 1% solution = 1 gram/100 ml = 10 mg/ml = 10,000 ug/ml [ug=mcg]. . . . People often dilute 1% solution with 99 mls of propylene glycol [dilution ratio of 99:1], to create a solution that is 100 micrograms per ml. The preventive dose of ivermectin for a 10 kg [22 lb] dog then would be .5 mls."
http://www.espomagazine.com/vet/apr96.htm
"As mentioned in that article, the dose of Ivermectin necessary to treat or prevent intestinal parasites is about 30 times the dose used to prevent heartworm disease. The dosage you listed, 0.1 cc per 10 pounds of body weight, is the dosage recommended for the prevention of intestinal parasites and heartworms [thus, it's 30 times higher than needed to prevent heartworms alone]. Therefore, if you wish to use the cattle wormer, Ivomec, as a heartworm preventative only, the amount needed would, indeed, be too minute to measure accurately. One way to solve the problem is to dilute a small amount of Ivomec in vegetable oil or propylene glycol (a solvent sometimes used to treat bloat in livestock). The vegetable oil tastes better, but the drug will mix better with propylene glycol because that is the same liquid used to dissolve the Ivermectin in a bottle of Ivomec.
"One dilution scheme which would minimize waste would involve using a 1 cc syringe and the more common 3 cc syringe. Draw up 0.1 cc of Ivomec., using the small syringe, and mix well with 3 cc of vegetable oil or propylene glycol [this is a dilution ratio of 30:1]. Using this diluted product, the heartworm preventative dose would be a familiar 0.1 cc per 10 pounds of body weight. A larger amount could be diluted and stored in the refrigerator for future use, but the length of time its potency would remain is unknown."
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How often do you give shots under the skin for flea control?
quote:
Originally posted by cswest
How often do you give shots under the skin for flea control?
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Unless I am missing something from that article it says to mix the ivermec 30 to 1 and then give it to get the dosing accurate...
but honestly .1cc is nto actually difficult at all to measure out by using a 1cc plunger (or smaller) Luckily i have the super small pipets in my science room I use to be even more precise but diluting it isn't really gonna make it more or less safe...
Just want to say thanks for all the input on this one very informative , i bought a 50ml bottle from tractor supply, and i am going to stick with the tenth of a cc per 10pounds of body weight, with some Mt. DEW mixed in to take away the taste and give it orally, i also like to use nemex wormer every other month to reduce the exposure to the ivermectine so thanks again to everyone for solid advice
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